个人简介

面向航空航天、医工交叉和工业生产等领域，一直从事生物细胞动态定量显微成像、无标记高通量流式细胞检测、非接触高精度表面微振动探测、高精度快速表面缺陷检测等方面的科学研究。

研究方向

(1)基于数字全息显微成像的生物活细胞动态定量观测技术

(2)基于光学衍射层析成像的无标记高通量细胞识别与分选技术

(3)基于外差干涉的非接触高精度微振动探测技术

(4)基于多模态成像和人工智能算法的工业表面缺陷检测技术

教学工作

(1)教授研究生课程《光纤光学》

(2)教授本科生课程《光电子技术》

(3)教授本科生课程《光通信原理与技术》

学术成果

(1)Lu Xin, Wen Xiao, Huanzhi Zhang, Xiaosu Yi, Xiao ping Li,Feng Pan*, Classification of drug-resistant ovarian cancer cells using holographic flow cytometry through interpretable machine learning, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI, 2023, 12622, 185-189.

(2)Daniele Pirone, Lu Xin, Vittorio Bianco, Lisa Miccio, Wen Xiao, Leiping Che, Xiaoping Li, Pasquale Memmolo,Feng Pan*, Pietro Ferraro*. Identification of drug-resistant cancer cells in flow cytometry combining 3D holographic tomography with machine learning, Sensors and Actuators B: Chemical, 2023, 375, 132963.

(3)刘雅坤，肖文，车蕾平，李胤嘉，肖溪，王皓，潘锋*,基于数字全息显微层析的癌细胞空泡化成像研究（特邀）.中国激光，2023，50(9)，0907203.

(4)Xi Xiao, Leiping Che, Yinjia Li, Ran Peng, Mingqing Wang, Wen Xiao,Feng Pan*, Hao Wang*. Label-free observation of morphological alteration of irradiated-urothelial bladder carcinoma cells through digital holographic microscopy, 2022, Frontiers in Physics, 10, 925523.

(5)Yakun Liu, Wen Xiao, Huanzhi Zhang, Lu Xin, Xiaoping Li,Feng Pan*. Chemotherapy drug potency assessment method of ovarian cancer cells by digital holography microscopy, Biomedical Optics Express, 2022, 8(13), 4370-4385.

(6)辛露，肖文，刘雅坤，张焕芝，李小平，潘锋*，数字全息成像定量监测癌细胞凋亡过程形态变化（特邀）.光子学报，2022，51(10)，1017001.

(7)Daniele Pirone, Massimiliano Maria Villone, Pasquale Memmolo, Zhe Wang, Volodymyr Tkachenko, Wen Xiao, Leiping Che, Lu Xin, Xiaoping Li,Feng Pan*, Pietro Ferraro*, Pier Luca Maffettone*. On the hydrodynamic mutual interactions among cells for high-throughput microfluidic holographic cyto-tomography, 2022, Optics and Lasers in Engineering, 158, 107190.

(8)Lu Xin, Wen Xiao, Leiping Che, JinJin Liu, Lisa Miccio, Vittorio Bianco, Pasquale Memmolo, Pietro Ferraro, Xiaoping Li,Feng Pan*. Label-free assessment of the drug resistance of epithelial ovarian cancer cells in a microfluidic holographic flow cytometer boosted through machine learning, 2021, ACS omega, 6(46), 31046-31057.

(9)Wen Xiao, Zonghui Chen,Feng Pan*, Xueqin Hou, Hongliang Hao, Zhuang Guo. Full-field laser heterodyne imaging vibrometry using a CMOS–DVR system, 2021, Applied Optics, 27(60), 8513-8523.

(10)Wen Xiao, Lu Xin, Runyu Cao, Xintong Wu, Ran Tian, Leiping Che, Lianwen Sun, Pietro Ferraro,Feng Pan*. Sensing morphogenesis of bone cells under microfluidic shear stress by holographic microscopy and automatic aberration compensation with deep learning, 2021, Lab on a Chip, 7(21), 1385-1394.

(11)Leiping Che, Wen Xiao,Feng Pan*, Pietro Ferraro, Exploiting a holographic polarization microscope for rapid autofocusing and 3D tracking, 2020, Biomedical Optics Express, 12(11), 7150-7164.

(12)Che Leiping, Wen Xiao, Li Xiaoping, Jinjin Liu,Feng Pan*, Pietro Ferraro. Automatic removal of phase aberration in holographic microscopy for drug sensitivity detection of ovarian cancer cells, 2020, OSA Continuum, 7(3), 1856-1868.

(13)Feng Pan, Bin Dong, Wen Xiao, Pietro Ferraro. Stitching sub-aperture in digital holography based on machine learning, 2020, Optics Express, 5(23), 6537-6551.

荣誉获奖

(1)北京市高校英才计划

(2)军队科学进步二等奖

科研项目

(1)基于激光数字干涉的惯性器件面振动检测技术及应用研究,125万元，中国航天科技集团有限公司，2020.5-2024.12；

(2)基于定量相位显微成像的高通量高精度流式细胞检测，华为技术有限公司,195万元，2023.3-2024.10；

(3)基于高通量全息流式细胞显微技术的老年尿路上皮癌早筛方法研究,北京市自然科学基金委,30万元,2022.1-2023.12;

(4)钛合金齿轮槽螺栓预紧力非接触测量技术，中国航空工业集团公司，50万元，2021.6-2022.12；

(5)数字全息成像/靶向ABCG2-C421A耐药蛋白荧光成像多模态系统的子宫内膜癌化疗敏感性人工智能评估初步研究,北京市卫生健康委,39万元,2020.1-2022.12；

(6)基于数字全息的定量动态三维显微成像技术及生物医学应用研究,国家科学技术部,40万元,2020.1-2022.12;

(7)基于数字全息显微成像技术的生物细胞多模态无损测量方法研究,北京市自然科学基金委,20万元,2019.1-2021.12;

(8)基于主动声激励和面振动探测的原位结构缺陷检测技术,国家自然科学基金委,面上项目,56万元61775010,2018.1-2021.12;

(9)单光子时间分辨成像光谱测量系统显微部件设计与制造，国家科学技术部，270万元，2013.10-2018.9;

(10)数字全息合成孔径显微成像观测MEMS器件微形变的方法研究，国家自然科学基金委，72万元，2012.1-2015.12;

学术兼职

(1)中国仪器仪表学会空间仪器分会理事会理事

(2)《Frontier in photonics》期刊的客座编辑